Synthesis of oligoribonucleotides by the H-phosphonate approach using base-labile 2'-O-protective groups. III. Studies on kinetics of 2'-3' migration of aroyl groups

E. Rozners, A. Rekis, E. Bizdena

Technical University, Riga

Abstract: Kinetics of 2'-3' isomerisation of eighty N-acyl-5'-O-trithyl-2'-0-aroylnucleosides in a MeOH H20 (87:13) mixture at 24C was investigated by means of the reverse-phase-microcolumn liquid chromatography.

Russian Journal of Bioorganic Chemistry 1992, 18 (1):107-111

Full Text (PDF, in Russian)