Antigenic properties of the synthetic peptides of hexon and fiber of human adenovirus type 2

L. A. Tarassishin

Institute of Microbiology and Virology, Academy of Sciences of the Ukrainian SSR, Kiev

Abstract: Peptides corresponding to the N-terminal part of the hexon of human adenovirus type 2 and to the C-terminal part of the fiber of this virus were synthesized. Conjugated with BSA these peptides induced development of antibodies binding both with the peptides and the virus proteins. Sera to the hexon and fiber bound also with the synthetic peptides. Immunosorbents containing the antipeptide antibodies were prepared, and the hexon and fiber proteins were isolated from the adenovirus protein pool by the affinity chromatography.

Russian Journal of Bioorganic Chemistry 1991, 17 (8):1141-1144

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