Synthesis of potential lipoxygenase inhibitors from ricinoleic acid
D. A. Zabolotsky, G. I. Myagkova
M. V. Lomonosov Institute of Fine Chemical Technology, Moscow
Abstract: Several potential lipoxygenase inhibitors have been synthesized from (9Z)-12-hydro-xyoctadecen-9-oic (ricinoleic) acid methyl ester: methyl 8-(5'-hexyl-2'-furyl)octanoate, methyl (9Z)-12-azidooctadecen-9-oate, methyl (9Z)-12-methoxycarbonyloctadecen-9-oate to be studied as suicidal substrates.
Russian Journal of Bioorganic Chemistry 1991, 17 (8):1129-1132