Synthesis and substrate properties of C'-methyl-2'-deoxynucleoside 5'-triphosphates in DNA synthesis reactions catalysed by DNA polymerases

Z. G. Chidgeavadze, R. Sh. Beabealashvilli, N. Sh. Padyukova, S. N. Mikhailov

All-Union Cardiology Research Centre, Academy of Medical Sciences of the USSR, Moscow; V. A. Engelhardt Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow

Abstract: Starting from the earlier prepared 5'-C-methylthymidines and 3'-C-methyl-2'-de-oxyuridine, corresponding 5'-triphosphates were prepared and investigated in DNA synthesis reactions catalysed by DNA polymerases from different sources.

Russian Journal of Bioorganic Chemistry 1991, 17 (5):678-684

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