Fragments of biopolymers containing glycosyl phosphate residues. 6. Synthesis of α-D-galactose phosphodiesters, fragments of the phosphogalactans from Sporobolomyces yeasts and of the capsular antigen of Escherichia coli K52
N. S. Utkina, A. V. Nikolaev, V. N. Shibaev
N. D. Zelinsky Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow
Abstract: Syntheses of methyl 6-(α-D-galactopyranosyl phosphate)- and p-nitrophenyl 3-(α-D-galactopyranosyl phosphate)-α-D-galactopyranosides were performed through coupling of 2,3,4,6-tetra-O-benzoyl-α-D-galactopyranosyl hydrogenphosphonate with the partially acylated galactopyranosides, in the presence of trimethylacetyl chloride, followed by oxidation and debenzoylation. The data of 1H, 13C, and 31P NMR spectra of the synthesized phosphate diesters are reported.
Russian Journal of Bioorganic Chemistry 1991, 17 (4):531-539