Affinity chromatography of DNA fragments and P-modified oligonucleotides
T. V. Abramova, N. V. Arnirkhanov, V. V. Gorn, V. F. Zarytova, E. I. Frolova, I. G. Shishkina
Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Academy of Sciences of the USSR
Abstract: Affinity chromatography on covalently immobilized oligonucleotides has been used to isolate a fragment (302-mer) of the tick-borne encephalitis virus single-stranded DNA and an oligonucleotide (34-mer) from reaction mixtures, and to separate mixtures of octathymidylates modified at internucleotide phosphates into fractions of diastereoisomers.
Russian Journal of Bioorganic Chemistry 1991, 17 (2):232-240