New anthracycline antibiotics rubomycin M and rubomycin N

V. B. Zbarski, E. I. Lazhko, N. P. Potapova, E. V. Fomicheva, T. P. Saburova

Institute of New Antibiotics, Academy of Medical Sciences of the USSR, Moscow

Abstract: Two new anthracycline antibiotics have been isolated in study of a rubomycin complex produced by the mutant strain Streptomyces coeruleorubidus, var. 2679. Both compounds are daunomycinone disaccharides, whose carbohydrate part is presented by daunoseamine glycosylated at 4'-position with 2-deoxyfucopyranose (rubomycin M) or with 2,6-dideoxygulopyranose (rubomycin N).

Russian Journal of Bioorganic Chemistry 1991, 17 (12):1698-1701

Full Text (PDF, in Russian)