Synthesis, cloning and sequencing of the human α1-antitripsin cDNA

N. V. Tikunova, S. Ya. Golovin, N. N. Mikrjukov, Yu. L. Khripin, V. Yu. Tchernenco, V. G. Ivanov, A. A. Iljitcev, V. A. Petrenco

Research and Technology Institute of Biologically Active Substances, Berdsk; Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR, Kiev;Novosibirsk Medical Institute, Novosibirsk

Abstract: cDNA coding for the human α1-antitripsin (AAT) has been cloned and sequenced in the specially constructed plasmid vector pMG2. The cDNA codes for the full size amino acid sequence of the AAT M1-allele and the leader sequence.

Russian Journal of Bioorganic Chemistry 1991, 17 (12):1694-1697

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