Atrial natriuretic peptides. IV. Synthesis and study of short analogues

M. V. Ovchinnikov, Z. D. Bespalova, S. V. Zhukovski, N. F. Sepetov, I. V. Revenko

Cardiology Research Centre, Academy of Medical Sciences of the USSR, Moscow

Abstract: New analogues of atrial peptides of rat were synthesized by classical methods of peptide chemistry in solution. They contain a D-amino acid residue in the C-terminal part and a residue of mercaptopropionic acid in the N-terminal part of the molecule. Biological activity of the new analogues was studied.

Russian Journal of Bioorganic Chemistry 1991, 17 (10):1424-1432

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