The hidden symmetry of the genetic code and rules of amino acid interactions
G. I. Chipens
Institute of Organic Synthesis, Latvian Academy of Sciences, Riga
Abstract: Natural amino acids having common antiamino acids are divided into families and groups according to the algorithm of the genetic code (a-n-ñ-ā, amino acid-codon-antico-don-antiamino acid). Members of these groups are placed symmetrically in the structure of the genetic code. In the course of evolution, those point mutations are predominantly accepted retained. In homologous proteins of philogenetically related organisms which lend to amino acids belonging to one family or group and having common antiamino acids. This assumption is in agreement with L.B. Mekler's theory (1969) of the amino acid interaction code a-ā.
Russian Journal of Bioorganic Chemistry 1991, 17 (10):1335-1346