Reversed-phase high performance liquid chromatography of p-polyfluoroalkoxy(thio)derivatives of phenylalanine

S. V. Galushko, M. V. Grygorieva, M. T. Kolytcheva, I. I. Gerus, Yu. L. Yagupolsky, V. P. Kuhar

Institute of Bioorganic Chemistry, Academy of Sciences of Ukrainian SSR, Kiev

Abstract: The chromatographic behaviour of some p-polyfluoroalkoxy(thio)derivatives of phenylalanine on an octadecyl stationary phase was studied. The influence of different fluorine-containing groups on the retention parameters and their correlation with the hydrophobicity constants of the substituents were found.

Russian Journal of Bioorganic Chemistry 1990, 16 (8):1024-1027

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