The chemical-enzymatic synthesis of branched O-specific polysaccharides of Salmonella serogroup C2 and C3

T. N. Druzhinina, O. V. Sizova, V. N. Shibaev

N. D. Zelinsky Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow

Abstract: The possibility of chemical-enzymatic synthesis of branched polysaccharides was demonstrated with the enzymes from Salmonella newport and S. kentucky using synthetic polyprenyl pyrophosphate oligosaccharides. Formation of polymers with αl-2-, β1-2-α1-4- and β1-4-linkages between glucose residues in the branch and galactose residues of the main chain was shown.

Russian Journal of Bioorganic Chemistry 1990, 16 (6):822-829

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