SYNTHESIS OF D- AND L- erythro -THIOGLUCOCEREBROSIDES
V. V. BESSONOV, A. S. BUSHNEV, E. V. KHLOPOTOVA, E. N. ZVONKOVA
M. V. Lomonosov Institute of Fine Chemical Technology, Moscow
Abstract: D- and L-erythro-1-β-D-glucopyranosyl-2-stearoyl-1-deoxy-1-thiosphinganmes have been synthesized using racemic cis-4-iodomethyl-5-pentadecyl-2-phenyl-Δ2-oxazoline and tetraacetyl-β-D-thioglucose as starting compounds. The optically active diastereoisomers were separated by column liquid chromathography.
Russian Journal of Bioorganic Chemistry 1990, 16 (4):554-558