 |  |
A NEW REACTION OF 2 ,4 -DlKETOPYRIMIDINES
A. R. KHOMUTOV *, D. V'u. YAKOVLEV, R. M. KHOMUTOV
V. A. Engelghardt Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow; *A. N. Bakh Institute of Biochemistry, Academy of Sciences of the USSR, Moscow
Abstract: Within a wide pH ranges phosphonous acid selectively modifies 2.4-diketopyrimidi-nes (but not cytidine or purines) by reducing C-5 — C-6 double bond. Possible applications of this reaction to the nucleic acids investigation are discussed.
Russian Journal of Bioorganic Chemistry 1990, 16 (3):427-429