ACTIVATION OF 5-LIPOXYGENASE BY LIPOPHYLIC n -ALKYL-CONTAINING ACIDS IS AN ALLOSTERIC PROCESS

I. A. BUTOVICH, V. A. SOLOSHONOK, V. A. SOLODENKO,

V. P. KUKHAR

Institute of Bioorganic Chemistry,

Academy of Sciences of the Ukrainian SSR, Kiev

Abstract: Mechanism of the activation of 5-lipoxygenase (EC 1.13.11.12) has been investigated and shown to have the allosteric character. Limitations of the activator structure are formulated.

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Russian Journal of Bioorganic Chemistry 1990, 16 (2):270-271

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