Enantiospecific synthesis of methyl esters of R-(+)-α-lipoic acid and its optical antipode
A. G. Tolstikov, N. V. Khakhalina, E. E. Savateeva, L. V. Spirikhin, L. M. Khalilov, V. N. Odinokov, G.A. Tolstikov
Institute of Chemistry, Bashkirian Research Centre, Ural Division, Academy of Sciences of the USSR, Ufa
Abstract: A synthesis of optically active methyl esters of R-(+)-α-lipoic acid and its S-(—) α-enantiomer has been carried out from di-O-benzoyl-D- and L-arabinals via methyl-6R7- and methyl-6S,7-epoxyheptanoates.
Russian Journal of Bioorganic Chemistry 1990, 16 (12):1670-1674