Interaction of pyruvylamino acids with proton-donor solvents
R. D. Lampeka, I. O. Fritsky
T. G. Shevchenko State University, Kiev
Abstract: Structure of pyruvylamino acids has been studied by means of 1H and 13C NMR spectra in H2O, MeOH and DMSO. 13C-NMR-spectra in dimethylsulphoxide contained the set of signals' corresponding to the ketonic structure, whereas a new signal (~95 ppm) was detected in aqueous and methanol solutions with simultaneous increase of the other signals intensities. These effects were ascribed to the addition of a water or alcohol molecule to the ketogroup of the pyruvic residue. The equilibrium was characterised with the use of 1H NMR spectroscopy, the part of the solvating form being estimated as ca. 40%.
Russian Journal of Bioorganic Chemistry 1990, 16 (11):1563-1566