Glycosylation of oximes. A synthesis of dimethylglyoxime, benzophenonoxime and acetonoxime derivatives
Ya. V. Voznyi, S. V. Afanasyeva, A. A. Galoyan
Institute of Biochemistry, Academy of Sciences of the Armenian SSR, Yerevan
Abstract: Glycosides of oximes have been synthesized by the condensation of trimethylsilyl ethers of dimethylglyoxime, benzophenonoxime and acetonoxime with acetylated, 1,2-trans-glycosyl fluorides, the derivatives of α-manno-, β-galacto- and (β-glucopyranose being obtained. The synthesis of trimethylsilyl ethers of oximes and deacetylation of glyco-sides are described. The structure of glycosyl oximes was confirmed by the 13C NMR spectroscopy.
Russian Journal of Bioorganic Chemistry 1990, 16 (10):1398-1401